Basic Information
| LncRNA/CircRNA Name | ANRIL |
| Synonyms | CDKN2B-AS1, CDKN2B-AS, CDKN2BAS, NCRNA00089, PCAT12, p16AS |
| Region | GRCh38_9:21994778-22121097 |
| Ensemble | ENSG00000240498 |
| Refseq | NR_003529 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioblastoma |
| ICD-0-3 | NA |
| Methods | Microarray, qPCR |
| Sample | glioblastoma tissues, cell lines (A172, LN229, LN18, T98G, U251, U87-MG) |
| Expression Pattern | up-regulated |
| Function Description | Silencing ANRIL, a GBM upregulated lncRNA, inhibited glioma cell proliferation and colony growth. |
| Pubmed ID | 30038703 |
| Year | 2018 |
| Title | Genetic Landscape of Long Noncoding RNA (lncRNAs) in Glioblastoma: Identification of Complex lncRNA Regulatory Networks and Clinically Relevant lncRNAs in Glioblastoma. |
External Links
| Links for ANRIL | GenBank HGNC NONCODE |
| Links for glioblastoma | OMIM COSMIC |