Basic Information
| LncRNA/CircRNA Name | LASTR |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | doxorubicin | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | fosters cancer |
| ICD-0-3 | NA |
| Methods | Luciferase reporter assay etc. |
| Sample | cell lines(MDA-MB-468, MDA-MB-231,BT-549), |
| Expression Pattern | up-regulated |
| Function Description | Hypoxia-induced lncRNA LASTR is upregulated in epithelial cancer.LASTR depletion affects splicing efficiency by regulating the function of the RNA-splicing factor SART3. |
| Pubmed ID | 32301977 |
| Year | 2020 |
| Title | Stress-induced lncRNA LASTR fosters cancer cell fitness by regulating the activity of the U4/U6 recycling factor SART3. |
External Links
| Links for LASTR | GenBank HGNC NONCODE |
| Links for fosters cancer | OMIM COSMIC |