Basic Information
| LncRNA/CircRNA Name | KRT7-AS |
| Synonyms | Keratin7-antisense |
| Region | GRCh38_12:52245048-52247448 |
| Ensemble | ENSG00000257671 |
| Refseq | NR_146274 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qRT-PCR, Western blotting, Luciferase reporter assay, RNA-seq |
| Sample | CRC cell lines (HCT-116, LoVo),cancer and adjacent normal tissues |
| Expression Pattern | up-regulated |
| Function Description | KRT7-AS promoted metastasis of CRC cells by regulating KRT7.KRT7-AS and KRT7 expression were significantly elevated in colon cancer tissues. |
| Pubmed ID | 31910722 |
| Year | 2020 |
| Title | Fusobacterium nucleatum Promotes Colorectal Cancer Metastasis by Modulating KRT7-AS/KRT7 |
External Links
| Links for KRT7-AS | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |