Basic Information
| LncRNA/CircRNA Name | KLF3-AS1 |
| Synonyms | NA |
| Region | GRCh38_4:38612701-38664883 |
| Ensemble | ENSG00000231160 |
| Refseq | NR_026804 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | esophageal squamous cell carcinoma |
| ICD-0-3 | NA |
| Methods | qPCR, Western blot, Luciferase reporter assay, RIP etc |
| Sample | cell lines(Eca109) |
| Expression Pattern | down-regulated |
| Function Description | lncRNA KLF3-AS1 Is Poorly Expressed in ESCC, and KLF3-AS1 May Regulate KLF3 by Competitively Binding to miR-185-5p. |
| Pubmed ID | 32193151 |
| Year | 2020 |
| Title | lncRNA KLF3-AS1 Suppresses Cell Migration and Invasion in ESCC by Impairing miR-185-5p-Targeted KLF3 Inhibition |
External Links
| Links for KLF3-AS1 | GenBank HGNC NONCODE |
| Links for esophageal squamous cell carcinoma | OMIM COSMIC |