Basic Information
| LncRNA/CircRNA Name | KIAA0125 |
| Synonyms | NA |
| Region | GRCh38_14:105917979-105932642 |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colon cancer |
| ICD-0-3 | C18 |
| Methods | qRT-PCR , RNA-seq etc. |
| Sample | early-stage (ES) colon tumor tissues ,late-stage (LS) colon tumor tissues ,adjacent normal colon tissues |
| Expression Pattern | down-regulated |
| Function Description | KIAA0125 was significantly enriched in the PI3K-Akt signaling pathway and that MSTRG.35002.1 was markedly enriched in BMP signaling-related functions. Moreover, key miRNA-lncRNA-mRNA relationships, such as hsa-miR-29b-3p-KIAA0125-BCL2 and hsa-miR-29b-3p-MSTRG.35002.1-MMP2, were identified. Notably, the qPCR assay confirmed that KIAA0125 and MSTRG.35002.1 were significantly downregulated in both ES and LS colon tumor tissues compared with normal colon tissues. |
| Pubmed ID | 31043791 |
| Year | 2019 |
| Title | Whole Transcriptome Sequencing Identifies Crucial Genes Associated With Colon Cancer and Elucidation of Their Possible Mechanisms of Action |
External Links
| Links for KIAA0125 | GenBank HGNC NONCODE |
| Links for colon cancer | OMIM COSMIC |