Basic Information
LncRNA/CircRNA Name | KCNQ1OT1 |
Synonyms | KCNQ1OT1, KCNQ1-AS2, KCNQ10T1, Kncq1, KvDMR1, KvLQT1-AS, LIT1, NCRNA00012 |
Region | GRCh38_11:2608328-2699994 |
Ensemble | ENSG00000269821 |
Refseq | NR_002728 |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | Drug | |||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | breast cancer |
ICD-0-3 | C50 |
Methods | RNA-CISH etc. |
Sample | breast cancer tissues |
Expression Pattern | up-regulated |
Function Description | HOTAIR, H19 and KCNQ1OT1 had significantly higher expression levels in IBC than NA, and HOTAIR and H19 were both expressed more strongly in IBC than in DCIS tissues. |
Pubmed ID | 26323944 |
Year | 2015 |
Title | Long non-coding RNA chromogenic in situ hybridisation signal pattern correlation with breast tumour pathology. |
External Links
Links for KCNQ1OT1 | GenBank HGNC NONCODE |
Links for breast cancer | OMIM COSMIC |