Basic Information
| LncRNA/CircRNA Name | KCNK15-AS1 |
| Synonyms | NA |
| Region | GRCh38_20:44694892-44746021 |
| Ensemble | ENSG00000244558 |
| Refseq | NR_132377 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR, Western blot etc. |
| Sample | lung adenocarcinoma (LAD) tissues,cell lines(A549 and H460 ) |
| Expression Pattern | up-regulated |
| Function Description | KCNK15-AS1 was overexpressed in lung adenocarcinoma tissues compared with paracancerous normal tissues, and the high expression of KCNK15-AS1 was significantly associated with poor prognosis compared with the patients with low expression (P<0.001). |
| Pubmed ID | 31788071 |
| Year | 2019 |
| Title | Silencing of KCNK15-AS1 Inhibits Lung Cancer Cell Proliferation via Upregulation of miR-202 and miR-370 |
External Links
| Links for KCNK15-AS1 | GenBank HGNC NONCODE |
| Links for lung cancer | OMIM COSMIC |