Basic Information
| LncRNA/CircRNA Name | KB-208E9.1 |
| Synonyms | KB-208E9.1 |
| Region | GRCh38_22:23580880-23583859 |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | childhood acute lymphoblastic leukemia |
| ICD-0-3 | NA |
| Methods | qPCR etc. |
| Sample | cell lines (Reh, NALM-6) |
| Expression Pattern | up-regulated |
| Function Description | We validated that five such lncRNA transcripts overexpressed in pre-B cALL samples (RP11-137H2.4, RP11-68I18.10, AC156455.1, KB-208E9.1, and CTA-331P3.1) were also overexpressed in the Reh and NALM-6 pre-B cALL cell lines that had significant impacts on cancer hallmark traits such as cell proliferation, migration, apoptosis, and treatment response. |
| Pubmed ID | 27980230 |
| Year | 2017 |
| Title | A childhood acute lymphoblastic leukemia-specific lncRNA implicated in prednisolone resistance, cell proliferation, and migration. |
External Links
| Links for KB-208E9.1 | GenBank HGNC NONCODE |
| Links for childhood acute lymphoblastic leukemia | OMIM COSMIC |