Basic Information
| LncRNA/CircRNA Name | JPX |
| Synonyms | JPX, DCBALD06, ENOX, LINC00183, NCRNA00183 |
| Region | GRCh38_X:73944184-74070408 |
| Ensemble | ENSG00000225470 |
| Refseq | NR_024582 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | qPCR etc. |
| Sample | blood, HCC tissues |
| Expression Pattern | down-regulated |
| Function Description | JPX and XIST levels were significantly decreased in HCC and associated with histological grade and tumor-node-metastasis stage. Low JPX and XIST expression resulted in significantly poor overall survival of HCC. Moreover, plasma JPX levels in patients were lower than that in controls. |
| Pubmed ID | 27776968 |
| Year | 2017 |
| Title | Downregulation of long non-coding RNAs JPX and XIST is associated with the prognosis of hepatocellular carcinoma. |
External Links
| Links for JPX | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |