Basic Information
| LncRNA/CircRNA Name | IRAIN |
| Synonyms | IRAIN, IGF1R-AS |
| Region | GRCh38_15:98645863-98651221 |
| Ensemble | NA |
| Refseq | NR_126453 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR, RNAi, Cell proliferation assay, Cell migration assay etc. |
| Sample | NSCLC tissues, cell line (A549) |
| Expression Pattern | up-regulated |
| Function Description | Here, we demonstrated IRAIN as a tumor promoter in NSCLC. Its expression level was remarkably upregulated in NSCLC tissues and connected with tumor size and smoking status. Knockdown of IRAIN suppressed NSCLC cells proliferation in vitro. |
| Pubmed ID | 26722412 |
| Year | 2015 |
| Title | A novel long noncoding RNA IRAIN regulates cell proliferation in non small cell lung cancer. |
External Links
| Links for IRAIN | GenBank HGNC NONCODE |
| Links for non small cell lung cancer | OMIM COSMIC |