Basic Information
LncRNA/CircRNA Name | INXS |
Synonyms | ABALON, INXS |
Region | GRCh38_20:31721507-31723409 |
Ensemble | ENSG00000281376 |
Refseq | NR_131907 |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | apoptosis | Drug | ||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | liver cancer |
ICD-0-3 | C22.0 |
Methods | qPCR, RACE-PCR etc. |
Sample | cell lines (THLE-3, HepG2) |
Expression Pattern | down-regulated |
Function Description | Tumor cell lines from kidney, liver, breast and prostate showed an endogenous INXS expression that was 5- to 9-fold lower compared with non-tumor cell lines derived from the same tissues. |
Pubmed ID | 24992962 |
Year | 2014 |
Title | Long non-coding RNA INXS is a critical mediator of BCL-XS induced apoptosis. |
External Links
Links for INXS | GenBank HGNC NONCODE |
Links for liver cancer | OMIM COSMIC |