Basic Information
| LncRNA/CircRNA Name | IGFL2-AS1 |
| Synonyms | NA |
| Region | GRCh38_19:46189166-46203083 |
| Ensemble | ENSG00000268621 |
| Refseq | NR_135234 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | RNA-seq, qPCR, in vitro knockdown |
| Sample | metastatic breast tumors and non-tumor tissue, cell lines (MCF-10A, MCF-10AT1 and MCF-10CA1a ) |
| Expression Pattern | down-regulated |
| Function Description | IGFL2-AS1 was the most significantly decreased. Our results indicate that this lncRNA plays a role in downregulating its nearest neighbor, IGFL1, and affects migration of breast cancer cells. |
| Pubmed ID | 28488769 |
| Year | 2017 |
| Title | Selective expression of long non-coding RNAs in a breast cancer cell progression model. |
External Links
| Links for IGFL2-AS1 | GenBank HGNC NONCODE |
| Links for breast cancer | OMIM COSMIC |