Basic Information
| LncRNA/CircRNA Name | IGF2AS |
| Synonyms | IGF2-AS, IGF2-AS1, IGF2AS, PEG8 |
| Region | GRCh38_11:2140501-2148666 |
| Ensemble | ENSG00000099869 |
| Refseq | NM_016412 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | wilms tumor |
| ICD-0-3 | C64.9 |
| Methods | qPCR, Northern blot etc. |
| Sample | Wilms tumor tissues |
| Expression Pattern | down-regulated |
| Function Description | IGF2-AS was expressed at levels comparable with IGF2 sense expression derived from promoters P1 and P2 in normal tissue and in breast, ovarian, and Wilms' tumor tissues. In Wilms' tumors that demonstrate maintenance of imprinting of IGF2, IGF2-AS was imprinted. |
| Pubmed ID | 12702581 |
| Year | 2003 |
| Title | Loss of imprinting of IGF2 sense and antisense transcripts in Wilms' tumor. |
External Links
| Links for IGF2AS | GenBank HGNC NONCODE |
| Links for wilms tumor | OMIM COSMIC |