Basic Information
| LncRNA/CircRNA Name | IGF2AS |
| Synonyms | IGF2-AS, IGF2-AS1, IGF2AS, PEG8 |
| Region | GRCh38_11:2140501-2148666 |
| Ensemble | ENSG00000099869 |
| Refseq | NM_016412 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | qPCR, Southern blot etc. |
| Sample | SMMC-7721 cell line |
| Expression Pattern | differential expression |
| Function Description | IGF-IR and IGF-IIR antisense genes could significantly restrain the malignant behavior of human hepatoma cells and might be useful in investigating a potential route for hepatocellular carcinoma gene therapy. |
| Pubmed ID | 12603530 |
| Year | 2003 |
| Title | Effects of insulin-like growth factors-IR and -IIR antisense gene transfection on the biological behaviors of SMMC-7721 human hepatoma cells. |
External Links
| Links for IGF2AS | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |