Basic Information
| LncRNA/CircRNA Name | IGF2AS |
| Synonyms | IGF2-AS, IGF2-AS1, IGF2AS, PEG8 |
| Region | GRCh38_11:2140501-2148666 |
| Ensemble | ENSG00000099869 |
| Refseq | NM_016412 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | liver cancer |
| ICD-0-3 | C22.0 |
| Methods | qPCR, Northern blot etc. |
| Sample | liver cancer tissues |
| Expression Pattern | up-regulated |
| Function Description | We further tested seven cell lines for the expression ofIGF2-AS and found that it was most highly expressed in the Hep 3B, compared with the other cell lines (NCI-H596, K-562, Raji, U-937, T-47D, and MCF7.Northern blotting using IGF2-AS cDNA probe demonstrated a major IGF2-AS transcript of 2.2 kb in Hep 3B cells. |
| Pubmed ID | 12702581 |
| Year | 2003 |
| Title | Loss of imprinting of IGF2 sense and antisense transcripts in Wilms' tumor. |
External Links
| Links for IGF2AS | GenBank HGNC NONCODE |
| Links for liver cancer | OMIM COSMIC |