Basic Information
| LncRNA/CircRNA Name | HULC |
| Synonyms | HULC, HCCAT1, LINC00078, NCRNA00078 |
| Region | GRCh38_6:8435568-9294133 |
| Ensemble | ENSG00000251164 |
| Refseq | NR_004855 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | liver cancer |
| ICD-0-3 | C22.0 |
| Methods | qPCR, Western blot, RIP |
| Sample | liver cancer tissues, cell line (hLCSC) |
| Expression Pattern | up-regulated |
| Function Description | Our results demonstrate HULC, MALAT1 and telomere repeat-binding factor 2 (TRF2) are highly expressed in human hepatocellular carcinoma tissues, and HULC plus MALAT1 overexpression drastically promotes the growth of liver cancer stem cells. HULC cooperates with MALAT1 to aggravate liver cancer stem cells growth through telomere repeat-binding factor 2 |
| Pubmed ID | 27782152 |
| Year | 2016 |
| Title | HULC cooperates with MALAT1 to aggravate liver cancer stem cells growth through telomere repeat-binding factor 2 |
External Links
| Links for HULC | GenBank HGNC NONCODE |
| Links for liver cancer | OMIM COSMIC |