Basic Information
| LncRNA/CircRNA Name | HULC |
| Synonyms | NA |
| Region | GRCh38_6:8435568-9294133 |
| Ensemble | ENSG00000251164 |
| Refseq | NR_004855 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | qPCR |
| Sample | breast cancer tissues,cell lines(MDA-MB-231, MDA-MB-453, MDA-MB-468, T-47D,MCF-7, ZR-75,SK-BR-3 ,MCF-14A) |
| Expression Pattern | differential expression |
| Function Description | Finally, HULC expression is controlled by miR-203,12 a microRNA that suppresses estrogen-induced survival, migration, and invasion of ER?-positive breast cancer cells possibly through forthright targeting of ER?. |
| Pubmed ID | 30957286 |
| Year | 2019 |
| Title | Expression of long noncoding RNAs in breast cancer in relation to reproductive factors and tumor characteristics. |
External Links
| Links for HULC | GenBank HGNC NONCODE |
| Links for breast cancer | OMIM COSMIC |