Basic Information
| LncRNA/CircRNA Name | HULC |
| Synonyms | NA |
| Region | GRCh38_6:8435568-9294133 |
| Ensemble | ENSG00000251164 |
| Refseq | NR_004855 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qRT-PCR, Western blot |
| Sample | GC tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | HULC was upregulated and miR-9-5p was downregulated in GC, and both were associated with clinicopathologic features of GC patients. HULC knockdown repressed GC progression at least partly by regulating miR-9-5p/MYH9 axis. |
| Pubmed ID | 31726371 |
| Year | 2020 |
| Title | LncRNA HULC promotes the progression of gastric cancer by regulating miR-9-5p/MYH9 axis |
External Links
| Links for HULC | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |