Basic Information
| LncRNA/CircRNA Name | HOXB-AS3 |
| Synonyms | NA |
| Region | GRCh38_17:48549630-48606414 |
| Ensemble | ENSG00000233101 |
| Refseq | NR_033201 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | lung cancer |
| ICD-0-3 | C34 |
| Methods | qRT-PCR, Western blot |
| Sample | lung cancer tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | inhibition of HOXB-AS3 was able to repress A549 and H1975 cell proliferation, cell colony formation ability and meanwhile, triggered cell apoptosis. |
| Pubmed ID | 32039488 |
| Year | 2020 |
| Title | lncRNA HOXB-AS3 exacerbates proliferation, migration, and invasion of lung cancer via activating the PI3K-AKT pathway |
External Links
| Links for HOXB-AS3 | GenBank HGNC NONCODE |
| Links for lung cancer | OMIM COSMIC |