Basic Information
| LncRNA/CircRNA Name | HOXA11-AS |
| Synonyms | HOXA11-AS, HOXA-AS5, HOXA11-AS1, HOXA11AS, HOXA11S, NCRNA00076 |
| Region | GRCh38_7:27184518-27189293 |
| Ensemble | ENSG00000240990 |
| Refseq | NR_002795 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qPCR etc. |
| Sample | CRC tissues, cell lines (HCT8, HCT116 and RKO) |
| Expression Pattern | down-regulated |
| Function Description | The results demonstrated that HOXA11-AS expression was decreased in the CRC tissues and cell lines compared with that of the controls. Clinicopathological analysis indicated that low HOXA11-AS expression was significantly correlated with tumor size, advanced tumor-node-metastasis stage, lymph node metastasis and carcinoembryonic antigen level of patients with CRC. |
| Pubmed ID | 27895785 |
| Year | 2016 |
| Title | Expression and clinicopathological significance of the lncRNA HOXA11-AS in colorectal cancer. |
External Links
| Links for HOXA11-AS | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |