Basic Information
| LncRNA/CircRNA Name | HOXA11-AS |
| Synonyms | NA |
| Region | GRCh38_7:27184518-27189293 |
| Ensemble | ENSG00000240990 |
| Refseq | NR_002795 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | Themozolomide | |
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioma |
| ICD-0-3 | NA |
| Methods | qPCR, Western blot |
| Sample | glioma tissues and cell lines( U251, H4 SW1783, LN230, NIHAS) |
| Expression Pattern | up-regulated |
| Function Description | The lncRNA HOXA11-AS and ATB were significantly upregulated in glioma tissue, promoting glioma progression by binding to miR-140-5p and miR-200a respectively |
| Pubmed ID | 30972632 |
| Year | 2019 |
| Title | lncRNA SNHG16 Exerts Oncogenic Functions in Promoting Proliferation of Glioma Through Suppressing p21. |
External Links
| Links for HOXA11-AS | GenBank HGNC NONCODE |
| Links for glioma | OMIM COSMIC |