Basic Information
| LncRNA/CircRNA Name | HOXA11-AS |
| Synonyms | NA |
| Region | GRCh38_7:27184518-27189293 |
| Ensemble | ENSG00000240990 |
| Refseq | NR_002795 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR etc. |
| Sample | GC tissues,cell lines(AGS (adenocarcinoma) and SNU-2 (carcinoma)) |
| Expression Pattern | up-regulated |
| Function Description | HOXA11-AS Was Upregulated in GC and Inversely Correlated with PTCSC3HOXA11-AS overexpression led to promoted migration and invasion of gastric cancer cells. In addition, HOXA11-AS overexpression reduced the effects of PTCSC3 overexpression. |
| Pubmed ID | 32368140 |
| Year | 2020 |
| Title | LncRNA PTCSC3 Alleviates the Postoperative Distant Recurrence of Gastric Cancer by Suppression of lncRNA HOXA12-AS |
External Links
| Links for HOXA11-AS | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |