Basic Information
| LncRNA/CircRNA Name | HOTTIP-005 |
| Synonyms | HOTTIP, HOXA-AS6, HOXA13-AS1, NCRNA00213 |
| Region | GRCh38_7:27198575-27207259 |
| Ensemble | ENSG00000243766 |
| Refseq | NR_037843 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | pancreatic cancer |
| ICD-0-3 | C25 |
| Methods | Microarray, qPCR etc. |
| Sample | pancreatic cancer tissues, cell lines (PANC-1, BxPC-3, Capan2, MIAPaCa-2, SW1990, and AsPC-1) |
| Expression Pattern | up-regulated |
| Function Description | Compared with the HPDE6 cells, all PC cell lines had higher HOTTIP-005, XLOC_006390, and RP11-567G11.1 expression. The most increased lncRNAs in PC tissues were HOTTIP-005, XLOC_006390, and RP11-567G11.1. Increased HOTTIP-005 and RP11-567G11.1 expression were poor prognostic factors for patients with PC. |
| Pubmed ID | 26447755 |
| Year | 2015 |
| Title | Expression profile of long non-coding RNAs in pancreatic cancer and their clinical significance as biomarkers. |
External Links
| Links for HOTTIP-005 | GenBank HGNC NONCODE |
| Links for pancreatic cancer | OMIM COSMIC |