Basic Information
| LncRNA/CircRNA Name | HOTTIP |
| Synonyms | NA |
| Region | GRCh38_7:27198575-27207259 |
| Ensemble | ENSG00000243766 |
| Refseq | NR_037843 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 |
| Methods | RNA-seq |
| Sample | NSCLC tissue |
| Expression Pattern | up-regulated |
| Function Description | HOTTIP was expressed in all tumor samples and was overexpressed in squamous cell carcinoma (p = 0.007) and in smokers (p = 0.018). |
| Pubmed ID | 30819158 |
| Year | 2019 |
| Title | Clinical significance of long non-coding RNA HOTTIP in early-stage non-small-cell lung cancer. |
External Links
| Links for HOTTIP | GenBank HGNC NONCODE |
| Links for non small cell lung cancer | OMIM COSMIC |