Basic Information
| LncRNA/CircRNA Name | HOTAIRM1 |
| Synonyms | HOTAIRM1, HOXA-AS1, HOXA1-AS1, NCRNA00179 |
| Region | GRCh38_7:27095647-27100265 |
| Ensemble | ENSG00000233429 |
| Refseq | NR_038366 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | head and neck cancer |
| ICD-0-3 | C76.0 |
| Methods | qPCR, Western blot, etc. |
| Sample | HNT tissues, cell lines(NP69, Tca-8113, TU177, HNE1, Fadu) |
| Expression Pattern | down-regulated |
| Function Description | HOTAIRM1 was confirmed as a tumor suppressor via sponging miR-148a and promote the expression of DLGAP1 |
| Pubmed ID | 29905017 |
| Year | 2018 |
| Title | HOTAIRM1 competed endogenously with miR-148a to regulate DLGAP1 in head and neck tumor cells. |
External Links
| Links for HOTAIRM1 | GenBank HGNC NONCODE |
| Links for head and neck cancer | OMIM COSMIC |