Basic Information
| LncRNA/CircRNA Name | AK130977 |
| Synonyms | NA |
| Region | GRCh38_20:36550794-36551444 |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | malignant pleural mesothelioma |
| ICD-0-3 | NA |
| Methods | Microarray, qPCR etc. |
| Sample | MPM tissues, cell lines (H28, H226, H2052, H2452, MSTO etc.) |
| Expression Pattern | up-regulated |
| Function Description | AK130977 and AX746718 were both found to be down-regulated via both microarray and RT-qPCR (AK130977 Microarray (MA) = -5.207, RT-qPCR = -1.6; AX746718 MA = -3.37, RT-qPCR = -4.6), with AK130977 demonstrating fairly small changes using RT-qPCR. Similarly, BX648695, AK129685, EF177379, AK054908, AK130275, AF268386 and NR_003584 all demonstrated consistent up-regulation using both microarrays and RT-qPCR. |
| Pubmed ID | 23976967 |
| Year | 2013 |
| Title | Long non coding RNAs (lncRNAs) are dysregulated in Malignant Pleural Mesothelioma (MPM). |
External Links
| Links for AK130977 | GenBank HGNC NONCODE |
| Links for malignant pleural mesothelioma | OMIM COSMIC |