Basic Information
| LncRNA/CircRNA Name | AB074278 |
| Synonyms | NA |
| Region | GRCh38_17:63039470-63041178 |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | urothelial cancer |
| ICD-0-3 | NA |
| Methods | Microarray, qPCR, RNAi, in vitro knockdown etc. |
| Sample | urothelial carcinoma of the bladder tissues |
| Expression Pattern | up-regulated |
| Function Description | AB074278 was chosen because it was significantly upregulated in all tumour phenotypes, strongly associated with tumour progression, and has a low protein coding potential score.AB074278 in apoptosis avoidance and the maintenance of a pro-proliferative state in cancer through a potential interaction with EMP1, a tumour suppressor and a negative regulator of cell proliferation. |
| Pubmed ID | 25165097 |
| Year | 2014 |
| Title | Identification of differentially expressed long noncoding RNAs in bladder cancer. |
External Links
| Links for AB074278 | GenBank HGNC NONCODE |
| Links for urothelial cancer | OMIM COSMIC |