Basic Information
| LncRNA/CircRNA Name | HOTAIR |
| Synonyms | HOTAIR, HOXAS, HOXC-AS4, HOXC11-AS1, NCRNA00072 |
| Region | GRCh38_12:53962308-53974956 |
| Ensemble | ENSG00000228630 |
| Refseq | NR_003716 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | esophageal squamous cell carcinoma |
| ICD-0-3 | NA |
| Methods | qPCR |
| Sample | esophageal squamous cell carcinoma tissues, blood |
| Expression Pattern | up-regulated |
| Function Description | The expression level of serum HOTAIR was significantly higher in ESCC patients compared with that of healthy controls (0.055?0.008, P<0.01 |
| Pubmed ID | 28376832 |
| Year | 2017 |
| Title | Serum HOTAIR as a novel diagnostic biomarker for esophageal squamous cell carcinoma |
External Links
| Links for HOTAIR | GenBank HGNC NONCODE |
| Links for esophageal squamous cell carcinoma | OMIM COSMIC |