Basic Information
| LncRNA/CircRNA Name | HOTAIR |
| Synonyms | HOTAIR, HOXAS, HOXC-AS4, HOXC11-AS1, NCRNA00072 |
| Region | GRCh38_12:53962308-53974956 |
| Ensemble | ENSG00000228630 |
| Refseq | NR_003716 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | adenocarcinoma of esophagogastric junction |
| ICD-0-3 | C16.0 |
| Methods | qPCR, Western blot |
| Sample | esophagogastric adenocarcinoma tissues |
| Expression Pattern | up-regulated |
| Function Description | HOTAIR was found to be up-regulated in higher grades of AEJ tissues compared to low grades and/or noncancerous tissues. |
| Pubmed ID | 28352764 |
| Year | 2016 |
| Title | Association of HOTAIR expression with PI3K/Akt pathway activation in adenocarcinoma of esophagogastric junction |
External Links
| Links for HOTAIR | GenBank HGNC NONCODE |
| Links for adenocarcinoma of esophagogastric junction | OMIM COSMIC |