Basic Information
| LncRNA/CircRNA Name | HOTAIR |
| Synonyms | HOTAIR, HOXAS, HOXC-AS4, HOXC11-AS1, NCRNA00072 |
| Region | GRCh38_12:53962308-53974956 |
| Ensemble | ENSG00000228630 |
| Refseq | NR_003716 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | qPCR etc. |
| Sample | serum |
| Expression Pattern | up-regulated |
| Function Description | We found that total HOTAIR was effectively amplified by most of the primers, suggesting the presence of HOTAIR in serum. The primer pair for 2-1 showed the highest amplification efficiency, and the PCR product was confirmed by gel detection and sequencing |
| Pubmed ID | 26033707 |
| Year | 2015 |
| Title | Circulating DNA of HOTAIR in serum is a novel biomarker for breast cancer. |
External Links
| Links for HOTAIR | GenBank HGNC NONCODE |
| Links for breast cancer | OMIM COSMIC |