Basic Information
| LncRNA/CircRNA Name | AB073614 |
| Synonyms | NA |
| Region | GRCh38_3:149173591-149175492 |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioma |
| ICD-0-3 | NA |
| Methods | qPCR, RNAi, Western blot, Cell proliferation assay etc. |
| Sample | glioma tissues, cell line (U251) |
| Expression Pattern | up-regulated |
| Function Description | We confirmed that AB073614 was significantly upregulated in glioma tissues and cell lines. In vitro studies demonstrated that knockdown of AB073614 inhibits U251 cell proliferation and migration. Moreover, knockdown of AB073614 could inhibit epithelial-mesenchymal transition (EMT) phenotype in glioma cells. |
| Pubmed ID | 27775800 |
| Year | 2016 |
| Title | Knockdown of long noncoding RNA AB073614 inhibits glioma cell proliferation and migration via affecting epithelial-mesenchymal transition. |
External Links
| Links for AB073614 | GenBank HGNC NONCODE |
| Links for glioma | OMIM COSMIC |