Basic Information
| LncRNA/CircRNA Name | HOTAIR |
| Synonyms | NA |
| Region | GRCh38_12:53962308-53974956 |
| Ensemble | ENSG00000228630 |
| Refseq | NR_003716 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | oral squamous cell carcinoma |
| ICD-0-3 | C06.9 |
| Methods | qRT-PCR, Western blot |
| Sample | OSCC tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | HOTAIR acted as a competitive endogenous RNA effectively sponging miR-326, thereby regulating the derepression of HOTAIR over-expression promoted the progression of OSCC.metastasis-associated gene 2 (MTA2). |
| Pubmed ID | 31995261 |
| Year | 2020 |
| Title | LncRNA HOTAIR promotes the invasion and metastasis of oral squamous cell carcinoma through metastasis-associated gene 2 |
External Links
| Links for HOTAIR | GenBank HGNC NONCODE |
| Links for oral squamous cell carcinoma | OMIM COSMIC |