Basic Information
| LncRNA/CircRNA Name | HORAS5 |
| Synonyms | linc00161, NCRNA00161, C21orf100, linc-USP16 |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | prostate cancer |
| ICD-0-3 | C61.9 |
| Methods | qPCR, Western blot, RNA-seq |
| Sample | PCa tissues, cell lines( LNCaP, C4-2) |
| Expression Pattern | up-regulated |
| Function Description | HORAS5 (aka linc00161, NCRNA00161, C21orf100, linc-USP16) was significantly up-regulated in all the three castration-resistant PDXs (4-130-fold; Fig. 1B). |
| Pubmed ID | 30776192 |
| Year | 2019 |
| Title | The long noncoding RNA HORAS5 mediates castration-resistant prostate cancer survival by activating the androgen receptor transcriptional program. |
External Links
| Links for HORAS5 | GenBank HGNC NONCODE |
| Links for prostate cancer | OMIM COSMIC |