Basic Information
| LncRNA/CircRNA Name | HMLINCRNA717 |
| Synonyms | HMlincRNA717, GACAT2, MTCL1-AS1, MTCL1AS1 |
| Region | GRCh38_18:8695856-8707621 |
| Ensemble | ENSG00000265962 |
| Refseq | NR_120598 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR, RIP etc. |
| Sample | gastric cancer tissues, cell lines (AGS, BGC-823, HGC-27, MGC-803, SGC-7901 etc.) |
| Expression Pattern | down-regulated |
| Function Description | The expression levels of HMlincRNA717 in five gastric cancer cell lines, AGS, BGC-823, HGC-27, MGC-803, and SGC-7901, were significantly downregulated than those in normal gastric mucosal epithelial cell line GES-1. More importantly, our results indicated that HMlincRNA717 expression levels were correlated with cancer distal metastasis, venous invasion, and nervous invasion. lncRNA-HMlincRNA717 may play crucial roles during cancer occurrence and progression and may be a new potential biomarker of early gastric cancer. |
| Pubmed ID | 24961350 |
| Year | 2014 |
| Title | Low expression of lncRNA-HMlincRNA717 in human gastric cancer and its clinical significances. |
External Links
| Links for HMLINCRNA717 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |