Basic Information
| LncRNA/CircRNA Name | HKLINCR1 |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | lung cancer |
| ICD-0-3 | C34 |
| Methods | qRT-PCR , RNA-seq , in vitro knockdown etc. |
| Sample | Non-small-cell lung cancer cell lines(H460, H1755 and A549) |
| Expression Pattern | up-regulated |
| Function Description | Depletion of HKlincR1 affected cell growth in multiple lung cancer cell lines, and led to disruption of genes involved in cell growth and viability. In addition, HKlincR1 expression was correlated with overall survival in lung adenocarcinoma patients.cHK-lincRNA ubiquitously expressed and rarely deleted, downregulated, or subject to epigenetic repression across a multitude of tumour tissue types. |
| Pubmed ID | 31089191 |
| Year | 2019 |
| Title | In Silico Prediction of Housekeeping Long Intergenic Non-Coding RNAs Reveals HKlincR1 as an Essential Player in Lung Cancer Cell Survival |
External Links
| Links for HKLINCR1 | GenBank HGNC NONCODE |
| Links for lung cancer | OMIM COSMIC |