Basic Information
| LncRNA/CircRNA Name | HIF1A-AS2 |
| Synonyms | HIF1A-AS2, 3'aHIF-1A, aHIF |
| Region | GRCh38_14:61715558-61751097 |
| Ensemble | ENSG00000258667 |
| Refseq | NR_045406 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | qPCR, Immunohistochemistry etc. |
| Sample | primary invasive breast cancer tissues |
| Expression Pattern | up-regulated |
| Function Description | We found a strong positive association between HIF-1alpha and sHIF-1alpha, sHIF-1alpha and aHIF, and an inverse correlation between HIF-1alpha /sHIF-1alpha and aHIF. aHIF transcript expression was associated with poor disease-free survival in univariate and multivariate analyses in this series of high-risk primary breast carcinomas. |
| Pubmed ID | 14580258 |
| Year | 2003 |
| Title | aHIF but not HIF-1alpha transcript is a poor prognostic marker in human breast cancer. |
External Links
| Links for HIF1A-AS2 | GenBank HGNC NONCODE |
| Links for breast cancer | OMIM COSMIC |