Basic Information
| LncRNA/CircRNA Name | HCG11 |
| Synonyms | HCG11, CTA-14H9.3, bK14H9.3 |
| Region | GRCh38_6:26521709-26527404 |
| Ensemble | ENSG00000228223 |
| Refseq | NR_026790 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | prostate cancer |
| ICD-0-3 | C61.9 |
| Methods | qPCR etc. |
| Sample | prostate cancer tissues |
| Expression Pattern | down-regulated |
| Function Description | We found that the expression levels of HCG11 in PCa tissues were significantly lower than those in non-tumor tissues in publically available databases and in human PCa samples. Our results showed the expression levels of HCG11 in patients with PCa were associated with the age, Lymph Node Status (LN status), preoperative PSA level, Gleason score, and biochemical recurrence (BCR). |
| Pubmed ID | 27522256 |
| Year | 2016 |
| Title | Downregulation of long non-coding RNA HCG11 predicts a poor prognosis in prostate cancer. |
External Links
| Links for HCG11 | GenBank HGNC NONCODE |
| Links for prostate cancer | OMIM COSMIC |