Basic Information
| LncRNA/CircRNA Name | HAR1A |
| Synonyms | NA |
| Region | GRCh38_20:63102205-63104386 |
| Ensemble | ENSG00000225978 |
| Refseq | NR_003244 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | qPCR, other |
| Sample | HCC tissues |
| Expression Pattern | down-regulated |
| Function Description | The expression levels of HAR1A and HAR1B were significantly lower in the HCC group, compared with the CHB and LC groups (P <.01). HAR1A and HAR1B were negatively associated with histologic grade and TNM (tumor/nodes/metastasis) stage (all P <.05). Univariable multivariable analysis showed that decreased HAR1A (HR = 0.753, P = .02) and HAR1B (HR = 0.551, P = .01) levels were independent predictors for shorter overall survival (OS) in HCC. |
| Pubmed ID | 30304523 |
| Year | 2019 |
| Title | Expression Analysis of Long Non-Coding RNA HAR1A and HAR1B in HBV-Induced Hepatocullular Carcinoma in Chinese Patients |
External Links
| Links for HAR1A | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |