Basic Information
| LncRNA/CircRNA Name | H2A/K |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | renal cancer |
| ICD-0-3 | C64.9 |
| Methods | qPCR, Cell proliferation assay etc. |
| Sample | renal cancer tissues, cell line (HEK293T) |
| Expression Pattern | differential expression |
| Function Description | Quantitative proteomic analysis indicated that the expression of mutant H2A/K lncRNAs resulted in the upregulation of many oncogenes, which promoted cell proliferation. Finally, the promotion of cell proliferation by mutant H2A/K lncRNAs (C290T, C228A and A45G) was confirmed using cell proliferation assays. |
| Pubmed ID | 26953487 |
| Year | 2016 |
| Title | H2A/K pseudogene mutation may promote cell proliferation. |
External Links
| Links for H2A/K | GenBank HGNC NONCODE |
| Links for renal cancer | OMIM COSMIC |