Basic Information
| LncRNA/CircRNA Name | H19 |
| Synonyms | H19, ASM, ASM1, BWS, D11S813E, LINC00008, NCRNA00008, WT2 |
| Region | GRCh38_11:1995176-2001470 |
| Ensemble | ENSG00000130600 |
| Refseq | NR_002196 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | qPCR etc. |
| Sample | breast cancer tissues |
| Expression Pattern | up-regulated |
| Function Description | The results revealed that the expression of H19 was significantly increased in BC tissues and plasma compared with healthy controls, and plasma H19 levels were significantly correlated with estrogen receptor, progesterone receptor, c-erbB-2 and lymph node metastasis. Furthermore, plasma H19 levels were significantly decreased in postoperative samples than preoperative samples. |
| Pubmed ID | 27540977 |
| Year | 2016 |
| Title | Circulating lncRNA H19 in plasma as a novel biomarker for breast cancer. |
External Links
| Links for H19 | GenBank HGNC NONCODE |
| Links for breast cancer | OMIM COSMIC |