Basic Information
| LncRNA/CircRNA Name | AK024898 |
| Synonyms | ACER2, ALKCDase2, ASAH3L |
| Region | GRCh38_9:19409059-19452020 |
| Ensemble | ENSG00000177076 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | Microarray, qPCR, RNAi, Western blot etc. |
| Sample | cell lines (MCF-7 and T-47D) |
| Expression Pattern | up-regulated |
| Function Description | From these 127 DE lncRNAs, we selected the top 25 most significant genes for further validation and analysis (electronic supplementary material, table S2). For 23 out of 25 (92%) of the lncRNAs tested, quantitative real-time PCR (qRTPCR) on cDNA templates confirmed the microarray results. |
| Pubmed ID | 28003470 |
| Year | 2016 |
| Title | Primate-specific oestrogen-responsive long non-coding RNAs regulate proliferation and viability of human breast cancer cells. |
External Links
| Links for AK024898 | GenBank HGNC NONCODE |
| Links for breast cancer | OMIM COSMIC |