Basic Information
| LncRNA/CircRNA Name | AB073614 |
| Synonyms | NA |
| Region | GRCh38_3:149173591-149175492 |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qPCR, Western blot |
| Sample | colorectal cancer tissues, cell lines (SW480 and HCT116) |
| Expression Pattern | up-regulated |
| Function Description | lncRNA AB073614 was highly expressed in the colorectal cancer tissues.lncRNA AB073614 can induce the expression of EMT cell markers and regulate the process of EMT of CRC cells through regulating the JAK/STAT3 pathway activation. |
| Pubmed ID | 29439310 |
| Year | 2018 |
| Title | LncRNA AB073614 induces epithelial-mesenchymal transition of colorectal cancer cells via regulating the JAK/STAT3 pathway. |
External Links
| Links for AB073614 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |