Basic Information
| LncRNA/CircRNA Name | H19 |
| Synonyms | H19, ASM, ASM1, BWS, D11S813E, LINC00008, NCRNA00008, WT2 |
| Region | GRCh38_11:1995176-2001470 |
| Ensemble | ENSG00000130600 |
| Refseq | NR_002196 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR etc. |
| Sample | cell lines (H929, U266 and 8226) |
| Expression Pattern | up-regulated |
| Function Description | the expression of lncRNA H19 was up-regulated in 80 patients with MM and MM cell lines by RT-PCR analysis.the expression level of H19 could assist clinical staging,and the severity of the disease could be roughly determined according to the amount of H19 expressed in the patient serum. |
| Pubmed ID | 29470951 |
| Year | 2018 |
| Title | Serum level of long noncoding RNA H19 as a diagnostic biomarker of multiple myeloma. |
External Links
| Links for H19 | GenBank HGNC NONCODE |
| Links for lung cancer | OMIM COSMIC |