Basic Information
| LncRNA/CircRNA Name | AK022159 |
| Synonyms | NA |
| Region | GRCh38_3:23438674-23440786 |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | pancreatic cancer |
| ICD-0-3 | C25 |
| Methods | qPCR etc. |
| Sample | pancreatic cancer tissues, cell lines (Sw1990, PANC-1, BXPC-6 etc.) |
| Expression Pattern | up-regulated |
| Function Description | We further confirmed the selected 6 up-regulation of LncRNAs in PC tissues and PC cell lines through qPCR. Comparing to 293T cells, the expression of LncRNA AF339813 was significantly increased about 10-fold in PANC-1 cells, 8-fold in SW1990 cells and 8.9-fold in BxCP-3 cells. The other 5 LncRNAs have a certain degree of up-regulation in PC cell lines. |
| Pubmed ID | 26045769 |
| Year | 2015 |
| Title | Downregulation of NUF2 inhibits tumor growth and induces apoptosis by regulating lncRNA AF339813. |
External Links
| Links for AK022159 | GenBank HGNC NONCODE |
| Links for pancreatic cancer | OMIM COSMIC |