Basic Information
| LncRNA/CircRNA Name | H19 |
| Synonyms | H19, ASM, ASM1, BWS, D11S813E, LINC00008, NCRNA00008, WT2 |
| Region | GRCh38_11:1995176-2001470 |
| Ensemble | ENSG00000130600 |
| Refseq | NR_002196 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR, other |
| Sample | blood |
| Expression Pattern | NA |
| Function Description | rs2067051 was associated with a significantly decreased risk of NSCLC in our population [AA vs. GG: adjusted odds ratio (OR) = 0.75, 95% confidence interval (CI)=0.60-0.93; Additive model: OR=0.79, 95%CI=0.67-0.93)]. rs217727 was related to significantly increased NSCLC susceptibility (TT vs. CC: OR=1.16, 95%CI=1.01-1.33; Additive model: OR=1.16, 95%CI=1.01-1.33). However, no significant association was observed between rs2839698, rs4929984 and NSCLC risk. |
| Pubmed ID | 31424642 |
| Year | 2019 |
| Title | Association Between H19 Polymorphisms and NSCLC Risk in a Chinese Population |
External Links
| Links for H19 | GenBank HGNC NONCODE |
| Links for non small cell lung cancer | OMIM COSMIC |