Basic Information
| LncRNA/CircRNA Name | H19 |
| Synonyms | NA |
| Region | GRCh38_11:1995176-2001470 |
| Ensemble | ENSG00000130600 |
| Refseq | NR_002196 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | urothelial cell carcinoma |
| ICD-0-3 | NA |
| Methods | RT-PCR etc. |
| Sample | UCC patients and control group |
| Expression Pattern | NA |
| Function Description | Patients with UCC carrying the H19 rs217727 CT + TT and rs2107425 CT + TT genetic variants had a high risk of developing muscle invasive tumors (pT2-T4).CT+TT polymorphisms of rs2107425 were associated with worse disease-specific survival in UCC patients aged older than 65 years. |
| Pubmed ID | 31013794 |
| Year | 2019 |
| Title | Effects of Long Noncoding RNA H19 Polymorphisms on Urothelial Cell Carcinoma Development |
External Links
| Links for H19 | GenBank HGNC NONCODE |
| Links for urothelial cell carcinoma | OMIM COSMIC |