Basic Information
| LncRNA/CircRNA Name | H19 |
| Synonyms | NA |
| Region | GRCh38_11:1995176-2001470 |
| Ensemble | ENSG00000130600 |
| Refseq | NR_002196 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | myeloid cells, dendritic cells, T cells and B lymphocytes | Survival | ||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qPCR, Microarray |
| Sample | colon tissues |
| Expression Pattern | up-regulated |
| Function Description | Among them, lncRNA H19 was up-regulated in colon tumours and correlated with poor patient prognosis. Collectively, we have been the first to demonstrate the temporal expression and function of lncRNAs in CRC initiation.These results provide novel diagnosis and therapy targets for CRC. |
| Pubmed ID | 30920116 |
| Year | 2019 |
| Title | Temporal expression and functional analysis of long non-coding RNAs in colorectal cancer initiation. |
External Links
| Links for H19 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |