Basic Information
| LncRNA/CircRNA Name | AK002107 |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | T cell | Survival | ||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | qPCR, Luciferase reporter assay, Western blot |
| Sample | HCC tissues,cell lines(MHCC97H, MHCC97L, SMMC7721, Hep3B,BEL7402) |
| Expression Pattern | up-regulated |
| Function Description | The expression of lncRNA AK002107 is frequently upregulated in HCC samples and cell lines. Patients with HCC who have elevated lncRNA AK002107 expression exhibit poorer overall survival and disease-free survival. |
| Pubmed ID | 30943320 |
| Year | 2019 |
| Title | The long noncoding RNA AK002107 negatively modulates miR-140-5p and targets TGFBR1 to induce epithelial-mesenchymal transition in hepatocellular carcinoma. |
External Links
| Links for AK002107 | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |