Basic Information
| LncRNA/CircRNA Name | GNAS-AS1 |
| Synonyms | NA |
| Region | GRCh38_20:58818919-58850903 |
| Ensemble | ENSG00000235590 |
| Refseq | NR_002785 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | nasopharyngeal cancer |
| ICD-0-3 | C11 |
| Methods | qPCR, Western blot etc |
| Sample | NPC tissues and normal tissues.Nasopharyngeal carcinoma tissue,cell lines(CNE-1, CNE-2, SUNE-1) |
| Expression Pattern | up-regulated |
| Function Description | GNAS-AS1 was upregulated in NPC. GNAS-AS1 promoted cell proliferation, cell migration, and cell invasion in vitro. GNAS-AS1 exerted its function by regulating Wnt/?-catenin pathway. GNAS-AS1 functioned as an oncogenic role via mediating ?-catenin expression. |
| Pubmed ID | 32271425 |
| Year | 2020 |
| Title | Long Non-Coding RNA GNAS-AS1 Promotes Cell Migration and Invasion via Regulating Wnt/?-catenin Pathway in Nasopharyngeal Carcinoma |
External Links
| Links for GNAS-AS1 | GenBank HGNC NONCODE |
| Links for nasopharyngeal cancer | OMIM COSMIC |