Basic Information
| LncRNA/CircRNA Name | GHRLOS |
| Synonyms | NA |
| Region | GRCh38_3:10285754-10293449 |
| Ensemble | ENSG00000240288 |
| Refseq | NR_004431 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qPCR etc. |
| Sample | colorectal tissues |
| Expression Pattern | down-regulated |
| Function Description | GHRLOS is downregulated at a high frequency in human CRC tissues. To the best of our knowledge, for the first time, we revealed that GHRLOS may have clinical potential not only as a prospective biomarker for metastatic phenotype of CRC but also as a promising prognostic predictor in CRC. Our findings encourage further functional studies, which will explore its potential as a therapeutic target that may be used for the control of CRC metastasis and progression. |
| Pubmed ID | 29187879 |
| Year | 2017 |
| Title | Aberrant Expression of the Long Non-coding RNA GHRLOS and Its Prognostic Significance in Patients with Colorectal Cancer |
External Links
| Links for GHRLOS | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |